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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSPG4 All Species: 12.12
Human Site: S2203 Identified Species: 29.63
UniProt: Q6UVK1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UVK1 NP_001888.2 2322 250497 S2203 G E P G P M A S S P E P A V A
Chimpanzee Pan troglodytes XP_001144835 2322 250224 S2203 G E P G P M A S S P E P A V A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544783 2734 292279 G2618 G A P G P S P G P T A A S G G
Cat Felis silvestris
Mouse Mus musculus Q8VHY0 2327 252387 S2208 G Q P G Q A A S S P V P T A A
Rat Rattus norvegicus Q00657 2326 251891 S2207 G Q P G Q A A S S P M P T V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423277 2239 246390 I2133 I E A N M F S I I I P I C L I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696176 2389 266772 W2221 R F K G R N R W G N S N S I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609881 2381 270643 T2248 L P C P P D L T S V S P Q H H
Honey Bee Apis mellifera XP_396231 2180 244970 L2075 P A V G V M P L P R P P D H L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787050 2348 258563 L2171 D P F D F D G L T T A S T S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.7 N.A. 68.8 N.A. 83.2 83 N.A. N.A. 49.6 N.A. 30.5 N.A. 24.2 25.6 N.A. 27.4
Protein Similarity: 100 98.4 N.A. 74.8 N.A. 90.2 89.9 N.A. N.A. 66.1 N.A. 50.6 N.A. 44 43.3 N.A. 46.3
P-Site Identity: 100 100 N.A. 26.6 N.A. 60 66.6 N.A. N.A. 6.6 N.A. 6.6 N.A. 20 20 N.A. 0
P-Site Similarity: 100 100 N.A. 33.3 N.A. 66.6 73.3 N.A. N.A. 20 N.A. 20 N.A. 26.6 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 10 0 0 20 40 0 0 0 20 10 20 10 40 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 10 0 0 10 0 20 0 0 0 0 0 0 10 0 10 % D
% Glu: 0 30 0 0 0 0 0 0 0 0 20 0 0 0 0 % E
% Phe: 0 10 10 0 10 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 0 0 70 0 0 10 10 10 0 0 0 0 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 10 % H
% Ile: 10 0 0 0 0 0 0 10 10 10 0 10 0 10 10 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 10 20 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 10 30 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 10 0 10 0 0 0 10 0 10 0 0 0 % N
% Pro: 10 20 50 10 40 0 20 0 20 40 20 60 0 0 10 % P
% Gln: 0 20 0 0 20 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 10 0 0 0 10 0 10 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 10 40 50 0 20 10 20 10 0 % S
% Thr: 0 0 0 0 0 0 0 10 10 20 0 0 30 0 0 % T
% Val: 0 0 10 0 10 0 0 0 0 10 10 0 0 30 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _